Publications - 2007

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Powers KA, Miller WC, Pilcher CD, Mapanje C, Martinson FEA, Fiscus SA, Chilongozi D, Namakhwa D, Gama S, Price M, Galvin S, Hoffman I and Cohen MS. A risk score algorithm for detecting acute HIV-1 infection in an African STI clinic. AIDS. 2007 Oct 18. 21(16):2237-42. Abstract

Borrow P and Bhardwaj N. Innate immune responses in primary HIV-1 infection. Current Opinion in HIV and AIDS. 2008 Jan;3(1):36-44.

Hovav AH, Panas MW, Osuna CE, Cayabyab MJ, Autissier P, Letvin NL. The impact of a boosting immunogen on the differentiation of secondary memory CD8+ T cells. Journal of Virology. 2007 Dec. 81(23): 12793-802. Abstract

Hovav AH, Panas MW, Rahman S, Sircar P, Gillard G, Cayabyab MJ, Letvin NL. Duration of Antigen Expression In Vivo following DNA Immunization Modifies the Magnitude, Contraction, and Secondary Responses of CD8+ T Lymphocytes. Journal of Immunology. 2007 Nov 15. 179(10): 6725-33. Abstract

Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD. Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science. 2007 Sep 28. 317(5846): 1930-4. Abstract

Li Y, Migueles SA, Welcher B, Svehla K, Phogat A, Louder MK, Wu X, Shaw GM, Connors M, Wyatt RT, Mascola JR. Broad HIV-1 neutralization mediated by CD4-binding site antibodies. Nat Med. 2007 Sep. 13(9):1032-4.  Abstract

Pilcher CD, Joaki G, Hoffman IF, Martinson FEA, Mapanje C, Stewart PW, Powers KA, Galvin S, Chilongozi D, Gama S, Price MA, Fiscus SA, and Cohen MS. Amplified transmission of HIV-1: Comparison of HIV-1 concentrations in blood and semen in acute and chronic infection. AIDS. 2007 Aug 20. 21(13): 1723-30. Abstract

Jones LE and Perelson AS. Transient viremia and reservoir replenishment in HIV infected patients on antiretroviral therapy.
JAIDS. 2007 Aug 15. 45(5): 483-93. Abstract

Sun Y, Permar, SR, Buzby, AP, Letvin, NL. Memory CD4+ T-lymphocyte loss and dysfunction during primary simian immunodeficiency virus infection. J Virol. 2007 Aug; 81(15):8009-15. Epub 2007 May 23. Abstract

Hicks CB, Gay C, and Ferrari G. Acute HIV infection: the impact of anti-retroviral treatment on cellular immune responses.
Clinical and Experimental Immunology. 2007 Aug. 149(2): 211-6. Abstract

Fellay J, Shianna KV, Ge D, Colombo S, Ledergerber B, Weale M, Zhang K, Gumbs C, Castagna A, Cossarizza A, Cozzi-Lepri A, De Luca A, Easterbrook P, Francioli P, Mallal S, Martinez-Picado J, Miro JM, Obel N, Smith JP, Wyniger J, Descombes P, Antonarakis SE, Letvin NL, McMichael AJ, Haynes BF, Telenti A, Goldstein DB. A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1. Science. 2007 Jul 19 [Epub ahead of print]. Abstract

Kirchherr JL, Lu X, Kasongo W, Chalwe V, Mwananyanda L, Musonda RM, Xia SM, Scearce RM, Liao HX, Montefiori DC, Haynes BF, Gao F. High-throughput functional analysis of HIV-1 env genes without cloning. Journal of Virological Methods. 2007 Jul. 143(1): 104-11. Abstract

Qin, L, Greenland, JR, Moriya, C, Cayabyab, MJ, Letvin, NL. Effects of type I interferons on the adjuvant properties of plasmid GM-CSF in vivo. J. Virol. 2007 Oct 81(19):10606-13. Epub July 25. Abstract

Fellay J and Goldstein DB. Host genetics: fine-tuning innate signaling. Curr Biol. 2007 Jul 3. 17(13): R516-8. Abstract

Dhillon AK, Donners H, Pantophlet R, Johnson WE, Decker JM, Shaw GM, Lee FH, Richman DD, Doms RW, Vanham G, Burton DR. Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human Immunodeficiency Virus Type 1-infected donors. Journal of Virology. 2007 Jun. 81(12): 6548-62. Abstract

Gray ES, Moore PL, Choge IA, Decker JM, Bibollet-Ruche F, Li H, Leseka N, Treurnicht F, Mlisana K, Shaw GM, Karim SS, Williamson C, Morris L. Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection. Journal of Virology. 2007 Jun. 81(12):6187-96. Epub 2007 Apr 4. Abstract

Dey B, Pancera M, Svehla K, Shu Y, Xiang SH, Vainshtein J, Li Y, Sodroski J, Kwong PD, Mascola JR, Wyatt R. Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics and immunogenicity. Journal of Virology. 2007 Jun. 81(11): 5579-93. Abstract

Greenland, JR, Geiben, R, Ghosh, S, Pastor, WA, Letvin, NL. Plasmid DNA vaccine –elicited cellular immune responses limit in vivo vaccine antigen expression through Fas-mediated apoptosis. J. Immunol. 178: 5652-5658, 2007. Abstract

Wilson TJ, Presti RM, Tassi I, Overton ET, Cella M, Colonna M. FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection. Blood. 2007 May 1. 109(9):3786-93. Epub 2007 Jan 9. Abstract

Alam SM, McAdams M, Boren D, Rak M, Scearce RM, Gao F, Comacho ZT, Gewirth D, Kelsoe G, Chen P, Haynes BF. The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes. J. Immunol.178: 4424-35, 2007. Abstract

Kothe DL, Decker JM, Li Y, Weng Z, Bibollet-Ruche F, Zammit KP, Salazar MG, Chen Y, Salazar-Gonzalez JF, Moldoveanu Z, Mestecky J, Gao F, Haynes BF, Shaw GM, Muldoon M, Korber BT, Hahn BH. Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins. Virology. 2007 Mar 30. 360(1): 218-34. Abstract

Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, Xiang SH, Yang X, Zhang MY, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, Nabel GJ, Kwong PD. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature. 2007 Feb 15. 445(7129): 732-7. Abstract

Hovav AH, Cayabyab MJ, Panas MW, Santra S, Greenland J, Geiben R, Haynes BF, Jacobs WR Jr, Letvin NL. Rapid Memory CD8+ T-Lymphocyte Induction through Priming with Recombinant Mycobacterium smegmatis. Journal of Virology. 2007 Jan. 81(1): 74-83. Abstract

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