Raphael Dolin, MD


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Director of Clinical Trials Core

Raphael Dolin, MD is Dean for Academic and Clinical Programs and Maxwell Finland Professor of Medicine (Microbiology and Molecular Genetics) and is charged with developing and strengthening collaborative programs and initiatives among Harvard Medical School and its teaching affiliates and promoting a commitment to excellence in scholarship and ethical standards in academic endeavors and research.

Dr. Dolin received his B.A. from Harvard College and his M.D. from Harvard Medical School. He did his residency on the Harvard Service at Boston City Hospital and subsequently his fellowship in infectious disease at the Channing Laboratory of Brigham and Women's Hospital. After serving in various positions at the National Institute of Allergy and Infectious Diseases (NIAID) including Head of the Medical Virology Section, Laboratory of Clinical Investigation from 1974-1978, he began his academic career as a Professor of Medicine and Head of the Infectious Disease Unit at the University Of Vermont College Of Medicine. In 1982, he moved to the University of Rochester where he became Head of the Infectious Disease Unit and Professor of Medicine, and in 1989 became professor of microbiology and immunology. In 1991, Dr. Dolin was appointed Charles A. Dewey Professor of Medicine and Chair of the Department of Medicine, and Physician-in-Chief of Strong Memorial Hospital in Rochester, N.Y. Dr. Dolin was appointed Dean for Clinical Programs and Professor of Medicine at Harvard Medical School in 1998, and became Maxwell Finland Professor of Medicine in 1999. In 2001, Dr. Dolin became Maxwell Finland Professor of Medicine (Microbiology and Molecular Genetics), and in 2003 became the Dean for Academic and Clinical Programs.

A fellow of the American College of Physicians, Infectious Diseases Society of America, and Molecular Medicine Society, Dr. Dolin maintains membership in numerous professional organizations, including the American Association of Physicians, American Society for Clinical Investigation, American Federation for Medical Research, and American Society for Microbiology. He served on the Vaccine Advisory Panel and the Enteric Disease Review Board of the NIAID, as well as the AIDS Vaccine Research Committee of the National Institutes of Health. Dr. Dolin is chair of the Board of Trustees of Harvard Clinical Research Institute and former chair of the Executive Committee of the NIAID AIDS Vaccine Evaluation Group. Currently, Dr. Dolin serves as the Chair of the Board of Scientific Counselors for the NIH Vaccine Research Center.

Dr. Dolin serves as co-editor of Principles and Practice of Infectious Diseases and AIDS Therapy. He is author of more than 200 articles, books, chapters, and reviews on issues relating to herpes simplex virus, non-bacterial gastroenteritis, respiratory viruses, and HIV. Dr. Dolin has a long-standing interest in laboratory and clinical investigations of viral pathogenesis, antiviral chemotherapy, and viral vaccines. He and his colleagues were the first to describe the Norwalk, Hawaii and Snow Mountain viruses of gastroenteritis and to investigate the pathophysiology of disease caused by these agents in humans. He has conducted large-scale clinical trials of antiviral drugs such as acyclovir, rimantadine and didanosine, as well as studies of live attenuated influenza virus and rotavirus vaccines. His major research interest currently is in the development and clinical study of candidate HIV vaccines. He is the principal investigator of the NIAID sponsored HIV Vaccine Trials Unit at Harvard Medical School, and the principal investigator of the Clinical Trials Core of the NIAID sponsored New England Regional Center of Excellence in Biodefense and Emerging Infectious Diseases (NERCE/BEID). He directs the Clinical Trials Core of the NIAID sponsored Center for HIV/AIDS Vaccine Immunology (CHAVI).